Rising THC Concentrations in Cannabis Pose Health Risks
The increasing potency of cannabis is raising concerns about its impact on human health. THC, the psychoactive compound in cannabis, has been linked to a range of negative effects, including addiction, psychosis, and cardiovascular problems.
Johnny Stack, a 24-year-old who died in 2019, is a tragic example of the devastating consequences of cannabis use. Johnny started using cannabis at 14 and became addicted to its potent THC content. He experienced severe paranoia, hallucinations, and eventually took his own life.
Researchers at Yale University are sounding the alarm about the rising THC concentrations in cannabis. “The marijuana and cannabis products that your grandparents may have used are very different from what’s out there now,” says Deepak Cyril D’Souza, MD, Albert E Kent Professor of Psychiatry at Yale School of Medicine.
The average THC content in cannabis has increased from 4% in 1995 to 17% in 2017, and some products contain as much as 90% THC. This is a significant concern, as THC is a potent psychoactive substance that can lead to addiction and psychosis.
Studies have shown that heavy and early use of cannabis is associated with an increased risk of developing schizophrenia, bipolar disorder, depression, and anxiety. Additionally, cannabis use has been linked to changes in brain structure, particularly in the prefrontal cortex, which is associated with decision-making and executive function.
The cardiovascular effects of cannabis are also a growing concern. Research has shown that cannabis can increase heart rate and blood pressure, which can lead to cardiovascular problems, especially in individuals with pre-existing conditions.
The commercialization of cannabis is also raising concerns. The industry is targeting young people with attractive packaging and flavors, which can lead to addiction. “The real issue is not legalization, but commercialization,” says D’Souza.
Researchers are calling for more studies to be conducted on the effects of cannabis on human health. “We need to understand the implications of cannabis on human health, particularly in young people,” says Joao De Aquino, MD, assistant professor of psychiatry.
The Yale Center for the Science of Cannabis and Cannabinoids is one of the first of its kind on the east coast, dedicated to conducting high-quality research on the drug. “We hope to be leaders here at Yale as we embark on a very important and grand social experiment,” says D’Souza.
